HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Methoxyethylamine → 3-(2-Fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethyl)-isonicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Methoxyethylamine | HCID 8018 | — |
| Edukt | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| Produkt | 3-(2-Fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethyl)-isonicotinamide | HCID 57649654 | — |
Reaktionsschritte
3-(2-Fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethyl)-isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.45 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.60 mmol of 2-methoxy-ethylamine. LC/MS [3.42 min; 402 (M+1)]
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08524911B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-d20ec6959203455cb629f9c31c5742cb |
| Quellennotiz | uspto-grants-2013_09 |