4-Piperidinecarboxamide → HCID 22558065, Verbindung
Reaktionsgleichung
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]([NH2:9])=[O:8])[CH2:3][CH2:2]1.[Cl:10][C:11]1[C:16]([O:17][CH3:18])=[CH:15][C:14]([C:19]2[CH:24]=[C:23]([CH2:25]Cl)[CH:22]=[CH:21][N:20]=2)=[CH:13][C:12]=1[O:27][CH3:28]>>[Cl:10][C:11]1[C:16]([O:17][CH3:18])=[CH:15][C:14]([C:19]2[CH:24]=[C:23]([CH2:25][N:1]3[CH2:6][CH2:5][CH:4]([C:7]([NH2:9])=[O:8])[CH2:3][CH2:2]3)[CH:22]=[CH:21][N:20]=2)=[CH:13][C:12]=1[O:27][CH3:28]Komponenten
3
Versuchsvorschrift
Piperidine-4-carboxamide (301 mg) and 2-(4-chloro-3,5-dimethoxyphenyl) 4-chloromethyl pyridine (600 mg) were coupled in the same manner as described in Example 2 to give the title compound.
Quellen und Nachweise
- ORD-Eintrag
- ord-edee953360504ed3aa3980640f32975b
- Quelldatensatz
- uspto-grants-2003_08
- Patentnummer
- US06605620B1
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