HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-amino-N-(4-fluorophenyl)benzamide → 2-[[1-(4-Pyridyl)piperidin-4-ylcarbonyl]amino]-N-(4-fluorophenyl)benzamide Hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-amino-N-(4-fluorophenyl)benzamide | HCID 478822 | — |
| Edukt | 1-(4-Pyridinyl)-4-piperidinecarbonyl chloride | HCID 11183700 | — |
| Produkt | 2-[[1-(4-Pyridyl)piperidin-4-ylcarbonyl]amino]-N-(4-fluorophenyl)benzamide Hydrochloride | HCID 18174451 | 35% |
Reaktionsschritte
Using the procedure described in Example 138, N-(4-fluorophenyl)-2-aminobenzamide (0.92 mmol) and N-(4-pyridyl)isonipecotoyl chloride (1.8 mmol), purifying with RPHPLC Method A, yielded 146 mg (35%) of the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06605626B2 |
| Quelldatensatz | uspto-grants-2003_08 |
| ORD ID | ord-86e6c28cd84f49d2a046ff5f7d42bbb9 |
| Quellennotiz | uspto-grants-2003_08 |