Benzyl Bromide → 2-[[(1-Benzylpyridinium-4-yl)carbonyl]amino]-N-(4-chlorophenyl)benzamide Bromide
Reaktionsgleichung
[N:1]1[CH:6]=[CH:5][C:4]([C:7]([NH:9][C:10]2[CH:25]=[CH:24][CH:23]=[CH:22][C:11]=2[C:12]([NH:14][C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)=[O:13])=[O:8])=[CH:3][CH:2]=1.[CH2:26]([Br:33])[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[Br-:33].[CH2:26]([N+:1]1[CH:6]=[CH:5][C:4]([C:7]([NH:9][C:10]2[CH:25]=[CH:24][CH:23]=[CH:22][C:11]=2[C:12]([NH:14][C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)=[O:13])=[O:8])=[CH:3][CH:2]=1)[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1Komponenten
3
Versuchsvorschrift
Using the procedure described in Example 26, Part B, 2-(4-pyridinecarbonyl)amino-N-(4-chlorophenyl)benzamide (500 mg, 1.42 mmol) and benzyl bromide (0.25 mL, 2.13 mmol) yielded 538 mg (73%) of the title compound.
Quellen und Nachweise
- ORD-Eintrag
- ord-bd68c99e2d9b42fb93d09692338120eb
- Quelldatensatz
- uspto-grants-2003_08
- DOI