HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Amino-2-ethyl-1,3-propanediol → N-(1,1-Bis-hydroxymethyl-propyl)-3-(2-fluoro-4-iodo-phenylamino)-isonicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Amino-2-ethyl-1,3-propanediol | HCID 8282 | — |
| Edukt | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| Produkt | N-(1,1-Bis-hydroxymethyl-propyl)-3-(2-fluoro-4-iodo-phenylamino)-isonicotinamide | HCID 11518227 | — |
Reaktionsschritte
N-(1,1-Bis-hydroxymethyl-propyl)-3-(2-fluoro-4-iodo-phenylamino)-isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.33 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.47 mmol of 2-amino-2-ethyl-propane-1,3-diol. LC/MS [5.93 min; 460 (M+1)]
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08524911B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-fb86a7932c7a43d8b6f7464fc14498a0 |
| Quellennotiz | uspto-grants-2013_09 |