HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Iodo-o-toluidine → 2-Chloro-3-(2-fluoro-4-iodophenylamino)-isonicotinic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Iodo-o-toluidine | HCID 83221 | — |
| Edukt | 3-Chloro-2-fluoropyridine-4-carboxylic acid | HCID 12175428 | — |
| Edukt | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| Produkt | 2-Chloro-3-(2-fluoro-4-iodophenylamino)-isonicotinic acid | HCID 57649634 | — |
Reaktionsschritte
2-Chloro-3-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid was synthesized as outlined in General Method 1 and according to the procedure for the synthesis of intermediate 1 by reacting 4 mmol of 2-methyl-4-iodoaniline with 6 mmol 2-fluoro-3chloro-isonicotinic acid. LC/MS [10.25 min; 390.9 (M−1)-ESI-].
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08524911B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-fe2b8ef0267d4e8bbe3d06e9cad3585b |
| Quellennotiz | uspto-grants-2013_09 |