3-Aminopyridine → (2S)-2-[isobutyl(p-tolylsulfonyl)amino]-6-[[2-(3-pyridylamino)acetyl]amino]hexanoic acid

Beteiligte Stoffe

Reaktionsschritte

The title compound was prepared from Nα-isobutyl-Nα-(4-methylbenzenesulfonyl)-Nε-iodoacetyl-L-lysine (200 mg, 0.38 mmol, example 105, step B) by following the indications of general procedure H using DIEA (0.19 mL, 1.09 mmol) and 3-aminopyridine (175 mg, 1.36 mmol). The crude material was purified by preparative HPLC. The product was isolated as a solid (42 mg, 22% yield).

Herkunft & Nachweise