2-Aminopyridine → (2S)-2-[isobutyl(p-tolylsulfonyl)amino]-6-[[2-(2-pyridylamino)acetyl]amino]hexanoic acid

Beteiligte Stoffe

Reaktionsschritte

The title compound was prepared from Nα-isobutyl-Nα-(4-methylbenzenesulfonyl)-Nε-iodoacetyl-L-lysine (200 mg, 0.38 mmol, example 105, step B) by following the indications of general procedure H using DIEA (0.19 mL, 1.09 mmol) and 2-aminopyridine (170 mg, 1.31 mmol). The crude material was purified by preparative HPLC. The product was isolated as a solid (88 mg,.47% yield).

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