5-tert-Butyl-3-(2-chloro-benzyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine → 5-tert-Butyl-3-(2-chloro-benzyl)-7-isoxazolidin-2-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine

Beteiligte Stoffe

Reaktionsschritte

In analogy to the procedure described for the synthesis of 5-tert-butyl-3-(2-chloro-benzyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 1, step c), the title compound was prepared from 5-tert-butyl-7-chloro-3-(2-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and isoxazolidine hydrochloride and isolated as white solid (13.1 mg, 74%). MS (m/e): 373.4 (MH+).

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