HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(-)-3-Hydroxytetrahydrofuran → HCID 86683314, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (-)-3-Hydroxytetrahydrofuran | HCID 641512 | — |
| Edukt | 5-tert-Butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine | HCID 71558205 | — |
| Edukt | HCID 178441789 | HCID 178441789 | — |
| Produkt | HCID 86683314 | HCID 86683314 | — |
Reaktionsschritte
In analogy to the procedure described for the synthesis of 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 61), the title compound was prepared from 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and (R)-tetrahydrofuran-3-ol and isolated as colorless gum. MS (m/e): 353.3 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08741906B2 |
| Quelldatensatz | uspto-grants-2014_06 |
| ORD ID | ord-00f85542af9c469b80734d6a43992148 |
| Quellennotiz | uspto-grants-2014_06 |