2-Methylpyridine-5-boronic acid → HCID 86670603, Verbindung
Reaktionsgleichung
Br[C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:8]([CH:11]=[O:12])=[CH:9][N:10]=2)[CH:7]=1.[CH3:13][C:14]1[N:19]=[CH:18][C:17](B(O)O)=[CH:16][CH:15]=1>>[CH3:13][C:14]1[N:19]=[CH:18][C:17]([C:2]2[CH:3]=[CH:4][C:5]3[N:6]([C:8]([CH:11]=[O:12])=[CH:9][N:10]=3)[CH:7]=2)=[CH:16][CH:15]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared by following the procedure as described for Intermediate 1 using 6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde and 6-methylpyridin-3-ylboronic acid. Yield: 40%; 1H NMR (DMSO-d6; 300 MHz): δ 10.0 (s, 1H), 9.74 (s, 1H), 8.79 (d, 1H, J=1.8 Hz), 8.38 (s, 1H), 7.93-7.78 (m, 4H), 7.33 (d, 1H, J=8.1 Hz), 2.66 (s, 3H); MS: m/z 238(M+1)+.
Quellen und Nachweise
- ORD-Eintrag
- ord-a5f7842e453e480292631b69d27613f8
- Quelldatensatz
- uspto-grants-2014_06
- DOI