HCID 23055952, Verbindung → HCID 67254977, Verbindung
Reaktionsgleichung
[CH2:1]([NH:4][C@@H:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH2:7][CH:6]1[Br:14])[CH:2]=[CH2:3].Br.CC(O)C>CC(OC)(C)C>[BrH:14].[CH2:1]([NH:4][C@@H:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH2:7][CH:6]1[Br:14])[CH:2]=[CH2:3]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 7.5 °C
Versuchsvorschrift
The obtained N-2-Propene-1-yl-2-bromo-(R)-aminoindan (5 g) in 100 ml of MTBE was added to 10 ml of 10% HBr/IPA solution and the reaction mixture was stirred at 5-10° C. for 30 min. The precipitated solid was filtered, washed with MTBE and dried to give 8.7 g of N-2-Propene-1-yl-2-bromo-(R)-aminoindan hydrobromide (90% yield). Mass spectrum: [M+1]+: 252