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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 403742Erstellt: 25. Oktober 2026

3-Methoxyphenyl isothiocyanate → (S)-Methyl 2-(6-(4-(3-(3-methoxyphenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate

https://huagongshe.com/reaction/403742

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-Methoxyphenyl isothiocyanateHCID 137832—
Edukt(S)-Methyl 2-(6-(4-(3-(2-fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 53303391—
Edukt(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
Produkt(S)-Methyl 2-(6-(4-(3-(3-methoxyphenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731453—

Reaktionsschritte

The compound of example 59 was prepared analogous to compound of example 51 by reaction of compound of example 6 with 3-methoxyphenyl isothiocyanate. The compound of example 59 was used directly without isolation for the preparation of compound of example 60.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08748426B2
Quelldatensatzuspto-grants-2014_06
ORD IDord-f0e963304e3b4230b6acceff940037b6
Quellennotizuspto-grants-2014_06