HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Chlorobenzoyl chloride → (S)-Methyl 2-(6-(4-(4-chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Chlorobenzoyl chloride | HCID 8501 | — |
| Edukt | (S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 123625862 | — |
| Edukt | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| Produkt | (S)-Methyl 2-(6-(4-(4-chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 53303633 | — |
Reaktionsschritte
The compound of example 113 was prepared analogous to compound of example 97 by reaction of compound of example 6 with 4-chlorobenzoyl chloride. The compound of example 113 was used directly without isolation for the preparation of compound of example 114.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08748426B2 |
| Quelldatensatz | uspto-grants-2014_06 |
| ORD ID | ord-a69cb6dc75c147a1bb67389bbb58db09 |
| Quellennotiz | uspto-grants-2014_06 |