(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-3-Methyl-2-(1-oxo-6-(4-(4-propylbenzamido)phenyl)isoindolin-2-yl)butanoic acid
Reaktionsgleichung
C(NC1C=CC(C2C=C3C(CN([C@@H](C(C)C)C(O)=O)C3=O)=CC=2)=CC=1)(=O)C1C=CC=CC=1.[CH3:33][CH:34]([CH3:68])[C@H:35]([N:40]1[CH2:48][C:47]2[C:42](=[CH:43][C:44]([C:49]3[CH:54]=[CH:53][C:52]([NH:55][C:56](=[O:66])[C:57]4[CH:62]=[CH:61][C:60]([CH2:63][CH2:64][CH3:65])=[CH:59][CH:58]=4)=[CH:51][CH:50]=3)=[CH:45][CH:46]=2)[C:41]1=[O:67])[C:36]([O:38]C)=[O:37]>>[CH3:68][CH:34]([CH3:33])[C@H:35]([N:40]1[CH2:48][C:47]2[C:42](=[CH:43][C:44]([C:49]3[CH:54]=[CH:53][C:52]([NH:55][C:56](=[O:66])[C:57]4[CH:58]=[CH:59][C:60]([CH2:63][CH2:64][CH3:65])=[CH:61][CH:62]=4)=[CH:51][CH:50]=3)=[CH:45][CH:46]=2)[C:41]1=[O:67])[C:36]([OH:38])=[O:37]Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The compound of example 170 was prepared analogous to compound of example 98 by hydrolysis of compound of example 169.