Glycine methyl ester hydrochloride → Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)acetate
Reaktionsgleichung
[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][N:7]([C@H:12](C(C)C)[C:13]([O:15][CH3:16])=[O:14])[C:8]2=[O:11])=[CH:4][CH:3]=1.Cl.COC(=O)CN>>[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][N:7]([CH2:12][C:13]([O:15][CH3:16])=[O:14])[C:8]2=[O:11])=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
The compound of example 332 was prepared analogous to compound of example 329 by reaction of the compound of example 328 and glycine methyl ester hydrochloride.
Quellen und Nachweise
- ORD-Eintrag
- ord-a98d817003a24bafaabbcf5931cf6cca
- Quelldatensatz
- uspto-grants-2014_06
- Patentnummer
- US08748426B2
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