HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(Trifluoromethyl)benzoyl chloride → Methyl 1-(1-oxo-6-(4-(4-(trifluoromethyl)benzamido)phenyl)isoindolin-2-yl)cyclobutanecarboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(Trifluoromethyl)benzoyl chloride | HCID 67607 | — |
| Edukt | Methyl 1-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)cyclobutanecarboxylate | HCID 67314591 | — |
| Edukt | (S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 123625862 | — |
| Produkt | Methyl 1-(1-oxo-6-(4-(4-(trifluoromethyl)benzamido)phenyl)isoindolin-2-yl)cyclobutanecarboxylate | HCID 53303003 | 83% |
Reaktionsschritte
The compound of example 579 was prepared analogous to compound of example 97 by reaction of compound of example 574 with 4-trifluoromethyl benzoyl chloride.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08748426B2 |
| Quelldatensatz | uspto-grants-2014_06 |
| ORD ID | ord-93c1668ad5e44f11bf06f5d854289b7d |
| Quellennotiz | uspto-grants-2014_06 |