4-(Dimethylamino)Benzaldehyde → n-(5-Carboxypentyl)-4-(4-(dimethylamino)styryl)pyridinium bromide

HRID 40447

Reaktionsgleichung

Reaktionsgleichung von HRID 40447
[CH3:1][N:2]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]=O)=[CH:6][CH:5]=1)[CH3:3].[Br-:12].[C:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][N+:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1C)([OH:15])=[O:14].N1CCCC[CH2:29]1>C(O)C>[Br-:12].[C:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][N+:21]1[CH:22]=[CH:23][C:24]([CH:29]=[CH:10][C:7]2[CH:6]=[CH:5][C:4]([N:2]([CH3:1])[CH3:3])=[CH:9][CH:8]=2)=[CH:25][CH:26]=1)([OH:15])=[O:14]

Komponenten

5

Edukt 3

HCID 74794-(Dimethylamino)BenzaldehydeHCID 8082PiperidineHCID 666435031-(5-Carboxy-pentyl)-2-methyl-pyridinium bromide

Produkt 1

HCID 66643380n-(5-Carboxypentyl)-4-(4-(dimethylamino)styryl)pyridinium bromide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
60 °C

Versuchsvorschrift

A mixture of 4-N,N-dimethylaminobenzaldehyde (3 g, 20 mmoles), N-(5-carboxy-pentyl)picolinium bromide (5.6 g, 20 mmoles) and piperidine (2 mL) in ethanol (100 mL) was heated at 60° C. overnight. The mixture was evaporated to dryness in vacuo. The residue was redissolved in methanol and then precipitated with ether to give the product (6.7 g).

Aufarbeitung

  1. customThe mixture was evaporated to dryness in vacuo
  2. dissolutionThe residue was redissolved in methanol
  3. customprecipitated with ether

Quellen und Nachweise

ORD-Eintrag
ord-af6963a81e4745939b0548827d31456a
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08530195B2

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