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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 40485Erstellt: 23. Oktober 2026

Chloromethyl pivalate → 3-[4-(3,3-Dimethyl-2-oxo-5-trifluoromethyl-2,3-dihydroindol-1-ylmethoxy)phenyl]hex-4-ynoic acid

https://huagongshe.com/de/reaction/40485

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktChloromethyl pivalateHCID 87885—
EduktMethyl 3-(4-hydroxyphenyl)hex-4-ynoateHCID 57835749—
Edukt3,3-Dimethyl-5-(trifluoromethyl)indolin-2-oneHCID 58031719—
Produkt3-[4-(3,3-Dimethyl-2-oxo-5-trifluoromethyl-2,3-dihydroindol-1-ylmethoxy)phenyl]hex-4-ynoic acidHCID 54766925—

Reaktionsschritte

Analogously to example 1, 3,3-dimethyl-5-trifluoromethyl-1,3-dihydroindol-2-one, chloromethyl pivalate and methyl 3-(4-hydroxyphenyl)hex-4-ynoate were used to obtain 3-[4-(3,3-dimethyl-2-oxo-5-trifluoromethyl-2,3-dihydroindol-1-ylmethoxy)phenyl]hex-4-ynoic acid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08530413B2
Quelldatensatzuspto-grants-2013_09
ORD IDord-a7437a70bed24e358008440ab46f21fe
Quellennotizuspto-grants-2013_09