2-Amino-5-chlorophenol → HCID 58117890, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[OH:9].[N:10]1(C(OC(C)(C)C)=O)[CH2:15][CH2:14][CH:13]([C:16]([O-])=O)[CH2:12][CH2:11]1>>[Cl:8][C:5]1[CH:6]=[CH:7][C:2]2[N:1]=[C:16]([CH:13]3[CH2:14][CH2:15][NH:10][CH2:11][CH2:12]3)[O:9][C:3]=2[CH:4]=1Komponenten
3
Versuchsvorschrift
500 mg 2-amino-5-chlorophenol and 800 mg mono-tert-butyl piperidine-1,4-dicarboxylate are heated to 200° C. in 4 ml polyphosphoric acid for 4 h. After cooling the reaction mixture is combined with ice water and stirred for 30 min. The precipitate is suction filtered, washed with water and dried. 850 mg product are obtained as the phosphate.
Aufarbeitung
- temperatureAfter cooling the reaction mixture
- filtrationfiltered
- washwashed with water
- customdried
Quellen und Nachweise
- ORD-Eintrag
- ord-bfc808555a5742d8a71cbeab465bfb8f
- Quelldatensatz
- uspto-grants-2014_06
- Patentnummer
- US08754073B2
Notizen zur Reaktion
Wird geladen…