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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 407088Erstellt: 25. Oktober 2026

(S)-(+)-Tetrahydrofurfurylamine → US10213427, Example 100

https://huagongshe.com/reaction/407088

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(S)-(+)-TetrahydrofurfurylamineHCID 641530—
Edukt2-(4-{3-[3-({[(2,2,2-Trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}phenyl)propanoic acidHCID 67980157—
ProduktUS10213427, Example 100HCID 57386930—

Reaktionsschritte

This compound was prepared by using procedure analogous to those described for the synthesis of Example 98, Step 9 starting from 2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}phenyl)propanoic acid and 1-[(25)-tetrahydrofuran-2-yl]methanamine. LCMS (M+H)+: m/z=567.3

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08754114B2
Quelldatensatzuspto-grants-2014_06
ORD IDord-0a413573f2d449a0b0b513fbe09f877a
Quellennotizuspto-grants-2014_06