Hydrochloric Acid → 3-Amino-2-(thiophen-3-yl)propanoic acid
Reaktionsgleichung
O=C1C2C(=CC=CC=2)C(=O)[N:3]1[CH2:12][CH:13]([C:18]1[CH:22]=[CH:21][S:20][CH:19]=1)[C:14]([O:16]C)=[O:15].Cl>>[NH2:3][CH2:12][CH:13]([C:18]1[CH:22]=[CH:21][S:20][CH:19]=1)[C:14]([OH:16])=[O:15]Komponenten
3
Versuchsvorschrift
To methyl 3-(1,3-dioxoisoindolin-2-yl)-2-(thiophen-3-yl)propanoate (E45) was added 6 N HCl, and the solution was refluxed for 4 hours. The solvents were evaporated to give 3-amino-2-(thiophen-3-yl)propanoic acid (E46).
Aufarbeitung
- temperaturethe solution was refluxed for 4 hours
- customThe solvents were evaporated
Quellen und Nachweise
- ORD-Eintrag
- ord-7de80a1bd882487a8a8e48bec9507312
- Quelldatensatz
- uspto-grants-2014_06
- Patentnummer
- US08759388B2
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