Triethylamine → 1-[2-((3,5-bis-trifluoromethyl-benzyl)-{(3S,5R)-1-[5-chloro-2-(4-hydroxy-piperidin-1-yl)-pyrimidin-4-yl]-5-ethyl-pyrrolidin-3-yl}-amino)-pyrimidin-5-yl]-3-methyl-imidazolidin-2-one
Reaktionsgleichung
C(O[C:6]([N:8]1[CH2:12][C@@H:11]([N:13]([CH2:27][C:28]2[CH:33]=[C:32]([C:34]([F:37])([F:36])[F:35])[CH:31]=[C:30]([C:38]([F:41])([F:40])[F:39])[CH:29]=2)[C:14]2[N:19]=[CH:18][C:17]([N:20]3[CH2:24][CH2:23][N:22]([CH3:25])[C:21]3=[O:26])=[CH:16][N:15]=2)[CH2:10][C@H:9]1[CH2:42][CH3:43])=O)(C)(C)C.[ClH:44].CCO[C:48]([CH3:50])=[O:49].FC(F)(F)C1C=[C:55](C=C(C(F)(F)F)C=1)[CH2:56][N:57]([C:65]1[N:70]=[CH:69][C:68](N2CCN(C)C2=O)=C[N:66]=1)[C@@H:58]1CN[C@H](CC)C1.CCN(CC)CC.C([O-])(O)=O.[Na+]>CCOC(C)=O.C(Cl)Cl>[F:36][C:34]([F:35])([F:37])[C:32]1[CH:33]=[C:28]([CH:29]=[C:30]([C:38]([F:40])([F:41])[F:39])[CH:31]=1)[CH2:27][N:13]([C@H:11]1[CH2:10][C@@H:9]([CH2:42][CH3:43])[N:8]([C:6]2[C:68]([Cl:44])=[CH:69][N:70]=[C:65]([N:57]3[CH2:58][CH2:50][CH:48]([OH:49])[CH2:55][CH2:56]3)[N:66]=2)[CH2:12]1)[C:14]1[N:19]=[CH:18][C:17]([N:20]2[CH2:24][CH2:23][N:22]([CH3:25])[C:21]2=[O:26])=[CH:16][N:15]=1Komponenten
8
Edukt 5
HCID 8471Triethylamine
HCID 516892Sodium Bicarbonate
HCID 21866389Hydrogen chloride-ethyl acetate
HCID 59614381(2R,4S)-4-{(3,5-bis-trifluoromethyl-benzyl)-[5-(3-methyl-2-oxo-imidazolidin-1-yl)-pyrimidin-2-yl]-amino}-2-ethyl-pyrrolidine-1-carboxylic acid tert-butyl ester
HCID 86648406(2R,4S)-4-{(3,5-Bis-trifluoromethyl-benzyl)-[5-(3-methyl-2-oxo-imidazolidin-1-yl)-pyrimidin-2-yl]-amino}-2-ethyl-pyrrolidine
