[ClH:1].[CH2:2]([NH:4][C:5](=[O:20])[CH:6]([C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)=[CH:10][CH:9]=1)[CH3:7])[CH3:3]>O1CCOCC1>[ClH:1].[CH2:2]([NH:4][C:5](=[O:20])[CH:6]([C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)=[CH:10][CH:9]=1)[CH3:7])[CH3:3]N-Ethyl-2-(4-piperidin-4-yl-phenyl)-propionamide hydrochloride is obtained by adding 4N HCl in dioxane to N-ethyl-2-(4-piperidin-4-yl-phenyl)-propionamide (VI.1). The mixture is stirred for 1 h and the solvent is removed in vacuo. The residue is taken up in diethyl ether, stirred for 20 min and the solvent is evaporated to yield the desired product.
Wird geladen…