HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → 3-Nitro-2,4-dimethyl-benzylamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | N-(3-Nitro-2,4-dimethyl-benzyl)-2,2,2-trifluoroacetamide | HCID 56840191 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 3-Nitro-2,4-dimethyl-benzylamine | HCID 56839972 | — |
Reaktionsschritte
A mixture of N-(3-nitro-2,4-dimethyl-benzyl)-2,2,2-trifluoroacetamide (1.53 g, 5.54 mmol), 4M NaOH-solution (6.9 mL, 28 mmol) and MeOH (30 mL) is refluxed for 2 h. Then the mixture is concentrated, diluted with water and extracted with EtOAc. The organic phase is dried with Na2SO4, filtered and concentrated.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08759537B2 |
| Quelldatensatz | uspto-grants-2014_06 |
| ORD ID | ord-c4c97e65efa749e0aa4adeb21e27d809 |
| Quellennotiz | uspto-grants-2014_06 |