HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Homoserine lactone hydrobromide → 3-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)-amino-gamma-butyrolactone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Homoserine lactone hydrobromide | HCID 73508 | — |
| Edukt | (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid | HCID 12135350 | — |
| Produkt | 3-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)-amino-gamma-butyrolactone | HCID 86584967 | — |
Reaktionsschritte
Following General Procedure A above using N-(3,5-difluorophenylacetyl)-L-alanine (Example B) and α-amino-γ-butyrolactone hydrobromide (Aldrich), the title compound was prepared as a solid having a melting point of 174-177° C. The reaction was monitored by tlc on silica gel (Rf=0.52 in 10% methanol/dichloromethane) and purification was by silica gel chromatography.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06559141B2 |
| Quelldatensatz | uspto-grants-2003_05 |
| ORD ID | ord-7c92c76fcf6340e381f63feea756c461 |
| Quellennotiz | uspto-grants-2003_05 |