3,4-Dichloroaniline → N-(3,4-dichlorophenyl)alanine Benzyl Ester

Beteiligte Stoffe

Reaktionsschritte

Following General Procedure AA above and using 3,4-dichloroaniline (Aldrich) and benzyl pyruvate (prepared by following General Procedure AO above using benzyl alcohol in place of iso-butanol), the title compound was prepared as an oil. The reaction was moniterd by tlc on silica gel (Rf=0.4 in 25% EtOAc/hexanes) and purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).

Herkunft & Nachweise