Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Decanoic Acid | HCID 2969 | — |
| Edukt | Dichloromethane | HCID 6344 | — |
| Edukt | Sodium Bicarbonate | HCID 516892 | — |
| Edukt | Chloromethyl chlorosulfate | HCID 2733556 | — |
| Katalysator | Tetrabutylammonium hydrogen sulfate | HCID 94433 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Chloromethyl decanoate | HCID 572571 | 100% |
Reaktionsschritte
Decanoic acid (0.2 gm, 1.2 mmol) was treated with 4 eq NaHCO3, 0.1 eq Bu4NHSO4 and, 1.2 eq ClCH2OSO2Cl in 1:1 CH2Cl2:H2O. The reaction was stirred vigorously at 0° C. for 30 min then room temperature (“RT”) for 3 hrs. Aqueous workup yielded chloromethyldecanoate (yield 100%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US06559164B1 |
|---|
| Quelldatensatz | uspto-grants-2003_05 |
|---|
| ORD ID | ord-01ffc514e7334937b06f28c9c7eef12f |
|---|
| Quellennotiz | uspto-grants-2003_05 |
|---|
