HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4,5-Dichloro-2-fluoroaniline → 4-[(3,4-Dichloro-6-fluorophenyl)amino]-6-nitroquinazoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4,5-Dichloro-2-fluoroaniline | HCID 223091 | — |
| Edukt | 4-Chloro-6-nitroquinazoline | HCID 11356257 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | 4-[(3,4-Dichloro-6-fluorophenyl)amino]-6-nitroquinazoline | HCID 15480998 | — |
Reaktionsschritte
3,4-Dichloro-6-fluoroaniline (1 equivalent) was reacted with 4-chloro-6-nitroquinazoline (3.5 equivalents), in iso-propylalcohol. After filtration, 4-[(3,4-dichloro-6-fluorophenyl)amino]-6-nitroquinazoline (compound 1) was obtained in 78% yield.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06562319B2 |
| Quelldatensatz | uspto-grants-2003_05 |
| ORD ID | ord-4a4f25d577154b809f69c5e6408ff8e5 |
| Quellennotiz | uspto-grants-2003_05 |