HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Leucine, N-carboxy-, N-benzyl ester, L- → 1-(Cbz-homo-leucinyl)-amino-3-(2-dibenzofuransulfonamido)-propan-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Leucine, N-carboxy-, N-benzyl ester, L- | HCID 74840 | — |
| Edukt | 8-Oxatricyclo(7.4.0.0,2,7)trideca-1(9),2(7),3,5,10,12-hexaene-4-sulfonyl chloride | HCID 2758030 | — |
| Edukt | 4-(3-Chloro-2-cyanophenoxy)benzenesulfonyl chloride | HCID 2776917 | — |
| Edukt | Z-HoLeu-OH | HCID 14484209 | — |
| Produkt | 1-(Cbz-homo-leucinyl)-amino-3-(2-dibenzofuransulfonamido)-propan-2-one | HCID 86585348 | — |
Reaktionsschritte
Following the procedure of Example 51, except 2-dibenzofuransulfonyl chloride for 4-(3-Chloro-2-cyano-phenoxy)-phenyl sulfonyl chloride and Cbz-homo-leucine for Cbz-leucine, the title compound was prepared: MS(ES) M+Na+=602.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06562842B2 |
| Quelldatensatz | uspto-grants-2003_05 |
| ORD ID | ord-d18b3837d9344ba5bef2f3e105d363b8 |
| Quellennotiz | uspto-grants-2003_05 |