Methanol → methyl (2S)-4-methyl-2-(methylamino)pentanoate
Reaktionsgleichung
[CH3:1][NH:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH:5]([CH3:7])[CH3:6].O1CCOC[CH2:12]1.CO>Cl>[CH3:12][O:9][C:8](=[O:10])[C@H:3]([CH2:4][CH:5]([CH3:7])[CH3:6])[NH:2][CH3:1]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
N-methyl-L-leucine (1.3 g, 8.95 mmol) was dissolved in 4M HCl, 1,4-dioxane (10 mL) and methanol (10 mL). The solution was stirred overnight at room temperature, then concentrated to afford the title compound as a white solid (100%). MS (ESI): 160.0 (M+H)+.
Aufarbeitung
- concentrationconcentrated
Quellen und Nachweise
- ORD-Eintrag
- ord-873da0f5b55f479496f9ff147aa8e0df
- Quelldatensatz
- uspto-grants-2003_05
- Patentnummer
- US06562842B2
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