Dichloromethane → N,N-Bis(2-chloroethyl)-N'-phenylcarbamimidic acid

HRID 413275Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 413275
S(Cl)([Cl:3])=O.O[CH2:6][CH2:7][N:8]([CH2:18]CO)[C:9]([NH:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:10].Cl[CH2:22][Cl:23]>>[Cl:3][CH2:6][CH2:7][N:8]([CH2:18][CH2:22][Cl:23])[C:9]([NH:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:10]

Komponenten

4

Edukt 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 22390756HCID 22390756, Verbindung

Produkt 1

HCID 247712N,N-Bis(2-chloroethyl)-N'-phenylcarbamimidic acid

Versuchsvorschrift

26.44 ml of thionyl chloride are added, at 0° C., to a solution of 0.173 mol of the product obtained in Step 1 in 100 ml of dichloromethane. After reacting for 4 hours at reflux and then for 12 hours at ambient temperature, the reaction mixture is concentrated under reduced pressure.

Aufarbeitung

  1. temperatureat reflux
  2. waitfor 12 hours at ambient temperature
  3. concentrationthe reaction mixture is concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-7795bb81d61a4f37b1b3c8f85dca6f17
Quelldatensatz
uspto-grants-2003_05
Patentnummer
US06566364B2

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