2-Phenylpropionic acid → 5-{N'-(2-phenylpropionyl)-L-alaninyl}-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

HRID 413858

Reaktionsgleichung

Reaktionsgleichung von HRID 413858
[C:1]1([CH:7]([CH3:11])[C:8](O)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:12][C@H:13]([C:15]([N:17]1[C:23](=[O:24])[CH:22]([CH3:25])[C:21]2[CH:26]=[CH:27][CH:28]=[CH:29][C:20]=2[C:19]2[C:30]([NH2:34])=[CH:31][CH:32]=[CH:33][C:18]1=2)=[O:16])[CH3:14]>>[C:1]1([CH:7]([CH3:11])[C:8]([NH:12][C@H:13]([C:15]([N:17]2[C:23](=[O:24])[CH:22]([CH3:25])[C:21]3[CH:26]=[CH:27][CH:28]=[CH:29][C:20]=3[C:19]3[C:30]([NH2:34])=[CH:31][CH:32]=[CH:33][C:18]2=3)=[O:16])[CH3:14])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Komponenten

3

Edukt 2

HCID 102962-Phenylpropionic acidHCID 697363355-(L-alaninyl)-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

Produkt 1

HCID 865925925-{N'-(2-phenylpropionyl)-L-alaninyl}-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one

Versuchsvorschrift

Following General Procedure C-P above using 2-phenylpropionic acid and 5-(L-alaninyl)-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one, as described in Example 7-B, the title compound was prepared. The molecular weight as determined by mass spectrometry (FD) was: 442 (M+H).

Quellen und Nachweise

ORD-Eintrag
ord-91c08f8d49ef4f11b27d2463cf90dc84
Quelldatensatz
uspto-grants-2003_05
Patentnummer
US06569851B1

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