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Potassium Carbonate → HCID 53670972, Verbindung

HRID 414653
Notizen
Druckvorschau

Reaktionsgleichung

Reaktionsgleichung von HRID 414653
C(=O)([O-])[O-].[K+].[K+].Br[CH:8]([CH3:19])[C:9]([O:11][CH2:12][CH2:13][O:14][N:15]=[C:16]([CH3:18])[CH3:17])=[O:10].[Cl:20][C:21]1[CH:34]=[C:33]([C:35]([F:38])([F:37])[F:36])[CH:32]=[CH:31][C:22]=1[O:23][C:24]1[CH:25]=[C:26]([OH:30])[CH:27]=[CH:28][CH:29]=1>CC(C)=O>[Cl:20][C:21]1[CH:34]=[C:33]([C:35]([F:36])([F:38])[F:37])[CH:32]=[CH:31][C:22]=1[O:23][C:24]1[CH:25]=[C:26]([CH:27]=[CH:28][CH:29]=1)[O:30][CH:8]([CH3:19])[C:9]([O:11][CH2:12][CH2:13][O:14][N:15]=[C:16]([CH3:18])[CH3:17])=[O:10]
KomponentenVersuchsvorschriftAufarbeitungQuellen und NachweiseNotizen zur Reaktion

Komponenten

5

Edukt 3

HCID 11430Potassium CarbonateHCID 129062603-[2-Chloro-4-(trifluoromethyl)phenoxy]phenolHCID 212815132-{[(Propan-2-ylidene)amino]oxy}ethyl 2-bromopropanoate

Produkt 1

HCID 53670972HCID 53670972, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

2.76 g of anhydrous potassium carbonate and 3.78 g of 2-isopropylideneaminooxy-ethyl 2-bromopropionate are added to a solution of 2.89 g of 3-(o-chloro-p-trifluoromethyl-phenoxy)-phenol in 40 ml of acetone and the mixture is heated at reflux temperature for 6 hours. The resulting solution is then concentrated to 30 ml and the concentrate is poured into 100 ml of water. The mixture is extracted three times with 80 ml of ethyl acetate each time, the combined organic phases are back-washed twice with 50 ml of water each time, the solvent is evaporated from the organic phase and there is obtained by distillation in a bulb-tube at 100°-170° C./0.05 mm Hg 2-isopropylideneaminooxy-ethyl 2-[3-(o-chloro-p-trifluoromethyl-phenoxy)-phenoxy]-propionate.

Aufarbeitung

  1. temperaturethe mixture is heated
  2. temperatureat reflux temperature for 6 hours
  3. concentrationThe resulting solution is then concentrated to 30 ml
  4. additionthe concentrate is poured into 100 ml of water
  5. extractionThe mixture is extracted three times with 80 ml of ethyl acetate each time
  6. washthe combined organic phases are back-washed twice with 50 ml of water each time
  7. customthe solvent is evaporated from the organic phase

Quellen und Nachweise

ORD-Eintrag
ord-ad27da8d106a4149845d09389e8ddf1c
Quelldatensatz
uspto-grants-1988_12
DOI
10.6084/m9.figshare.5104873.v1
Patentnummer
US04792616

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