Piperidine → HCID 178486868, Verbindung
Reaktionsgleichung
[NH:1]1CCCC[CH2:2]1.[NH2:7][C:8]1[CH:16]=[C:15]([O:17][CH3:18])[C:14]([OH:19])=[CH:13][C:9]=1[C:10](O)=[O:11].N1C=CC=NN=1>CO>[CH3:18][O:17][C:15]1[CH:16]=[C:8]2[C:9]([C:10]([OH:11])=[N:1][CH:2]=[N:7]2)=[CH:13][C:14]=1[OH:19]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 0 °C
Versuchsvorschrift
Piperidine (3 mL, 31 mmol) was added to a mixture of 2-Amino-5-hydroxy-4-methoxy-benzoic acid (8.1 g, 44.26 mmol) and triazine (5.38 g, 66.4 mmol) in MeOH (60 mL). The reaction was then heated to reflux and stir for 6 hours. The reaction was cool to 0° C. The product was isolated by filtration and washed with cold MeOH to give 6.37 g (33.2 mmol, 75%) of desired product.
Aufarbeitung
- temperatureThe reaction was then heated
- temperatureto reflux
- customThe product was isolated by filtration
- washwashed with cold MeOH
Quellen und Nachweise
- ORD-Eintrag
- ord-f0d62225581f45c8a0294bae9c5fb353
- Quelldatensatz
- uspto-grants-2012_01
- Patentnummer
- US08088766B2
Notizen zur Reaktion
Wird geladen…