Hydrochloric Acid → 1,3,5-Tris-(p-ethoxycarbonylanilino)-s-triazine

HRID 4156

Reaktionsgleichung

Reaktionsgleichung von HRID 4156
[NH2:1][C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][CH:3]=1.[N:13]1[C:20](Cl)=[N:19][C:17](Cl)=[N:16][C:14]=1Cl.Cl>C1(C)C(C)=CC=CC=1>[CH2:9]([O:8][C:6]([C:5]1[CH:4]=[CH:3][C:2]([NH:1][N:13]2[CH2:20][N:19]([NH:1][C:2]3[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][CH:3]=3)[CH2:17][N:16]([NH:1][C:2]3[CH:3]=[CH:4][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:11][CH:12]=3)[CH2:14]2)=[CH:12][CH:11]=1)=[O:7])[CH3:10]

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 2337BenzocaineHCID 7954Cyanuric chloride

Produkt 1

HCID 201527381,3,5-Tris-(p-ethoxycarbonylanilino)-s-triazineAusbeute 97 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7237O-XyleneLösungsmittel2×

Versuchsvorschrift

82.6 g of ethyl p-aminobenzoate and 30.75 g of cyanuric chloride in 1,500 ml of xylene were refluxed for 8 hours, hydrogen chloride escaping during this procedure. Thereafter, 1 liter of xylene was added, and the suspension, at 80°-90° C., was washed neutral with saturated sodium bicarbonate solution and then cooled to room temperature, and the product was filtered off over a glass suction filter. The white crystals obtained were washed with ethanol and dried. Mp: 218°-223° C.; yield: 97% of 1,3,5-tris-(p-ethoxycarbonylanilino)-s-triazine; ultraviolet (in ethanol): E1 cm1% =2,080 at 313 nm, E1 cm1% =699 at 218 nm.

Aufarbeitung

  1. washthe suspension, at 80°-90° C., was washed neutral with saturated sodium bicarbonate solution
  2. filtrationthe product was filtered off over a glass suction
  3. filtrationfilter
  4. customThe white crystals obtained
  5. washwere washed with ethanol
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-41d0738c14934a8d8d2f0c0151409174
Quelldatensatz
uspto-grants-1988_02
Patentnummer
US04724137

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