3-((Trifluoromethyl)thio)aniline → HCID 66619688, Verbindung
Reaktionsgleichung
[CH3:1][O:2][C:3]([C:5]1[C:6]([C:10]([OH:12])=O)=[CH:7][O:8][CH:9]=1)=[O:4].[F:13][C:14]([F:24])([F:23])[S:15][C:16]1[CH:17]=[C:18]([CH:20]=[CH:21][CH:22]=1)[NH2:19]>>[F:23][C:14]([F:13])([F:24])[S:15][C:16]1[CH:17]=[C:18]([NH:19][C:10]([C:6]2[C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:9][O:8][CH:7]=2)=[O:12])[CH:20]=[CH:21][CH:22]=1Komponenten
3
Versuchsvorschrift
Methyl 4-(3-(trifluoromethylthio)phenylcarbamoyl)furan-3-carboxylate is prepared from 4-(methoxycarbonyl)furan-3-carboxylic acid and 3-(trifluoromethylthio) aniline following Method G (yield=78%). 1H NMR (300 MHz, CHCl3) δ 11.66 (s, 1H), 8.29 (s, 1H), 8.22-8.09 (m, 1H), 7.96-7.82 (m, 2H), 7.50-7.37 (m, 2H), 3.99 (s, 3H); ESI(−) calcd. for C14H9F3NO4S (344.02). Found 344.0
Quellen und Nachweise
- ORD-Eintrag
- ord-557cbf7b56d349e6b8b02ad9bde101d1
- Quelldatensatz
- uspto-grants-2012_01