Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 416271Erstellt: 23. Oktober 2026

Acetylpyrazine → N-(2-Amino-phenyl)-4-{[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-ylamino]-methyl}-benzamide

https://huagongshe.com/de/reaction/416271

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktAcetylpyrazineHCID 30914—
Edukt2,4-Dimethyl-5-acetylthiazoleHCID 520888—
EduktN-(2-aminophenyl)-4-((4-(pyrazin-2-yl)pyrimidin-2-ylamino)methyl)benzamideHCID 44570891—
ProduktN-(2-Amino-phenyl)-4-{[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-ylamino]-methyl}-benzamideHCID 58930651—

Reaktionsschritte

Title compound was obtained according to the scheme 6 similarly to the compound 26a (Example 29) using instead of 1-pyrazin-2-yl-ethanone as the starting material 1-(2,4-dimethyl-thiazol-5-yl)-ethanone (Table 11). Characterization of the title compound is provided in the Table 12.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08088805B2
Quelldatensatzuspto-grants-2012_01
ORD IDord-ef4f9cd05f4448979bcd7209c64a4332
Quellennotizuspto-grants-2012_01