Hydrochloric Acid → Hydrochloric Acid
Reaktionsgleichung
[Si]([O:8][CH2:9][C@@H:10]([N:14](C)[C:15](=O)OC(C)(C)C)[CH2:11][CH:12]=[CH2:13])(C(C)(C)C)(C)C.[ClH:23]>CO>[CH3:15][NH:14][C@@H:10]([CH2:11][CH:12]=[CH2:13])[CH2:9][OH:8].[ClH:23]Komponenten
5
Edukt 2
Produkt 2
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of (S)-tert-butyl 1-(tert-butyldimethylsilyloxy)pent-4-en-2-yl(methyl)carbamate (3.4 g, 10.3 mmol) in methanol (10 mL) was added HCl (4.0 M in 1,4-dioxane, 25 mL, 0.10 mol). The resulting solution was stirred for 2 h. The solvent was removed, and the remaining residue was dried under vacuum to give (S)-2-(methylamino)pent-4-en-1-ol as a HCl salt, which was used without further purification. LRMS (M+H+) m/z 116.2.
Aufarbeitung
- customThe solvent was removed
- customthe remaining residue was dried under vacuum
Quellen und Nachweise
- ORD-Eintrag
- ord-ef233e9c95ec4382b5cbd25565daa0e6
- Quelldatensatz
- uspto-grants-2012_01
- Patentnummer
- US08088793B2
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