HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-methylpropyn-2-ylamine → 5,11-Dihydro-11-[[N-methyl(2-propynyl)amino]carbonyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-methylpropyn-2-ylamine | HCID 96160 | — |
| Edukt | 11-chlorocarbonyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | HCID 11043962 | — |
| Produkt | 5,11-Dihydro-11-[[N-methyl(2-propynyl)amino]carbonyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | HCID 20152918 | — |
Reaktionsschritte
Analogously to Example C, using 27.3 g (0.1 mol) of 11-chlorocarbonyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 7.0 g (0.1 mol) of N-methyl-propargylamine, 27 g (88% of theory) of the desired compound are obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04724236 |
| Quelldatensatz | uspto-grants-1988_02 |
| ORD ID | ord-40ce053f6f454522aede5b77a4a32553 |
| Quellennotiz | uspto-grants-1988_02 |