4-(2,2,2-Trifluoroethoxy)aniline → 2-(4-(2,2,2-Trifluoroethoxy)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione

Beteiligte Stoffe

Reaktionsschritte

This material was prepared as a light brown solid (0.685 g) in analogy to example 1 step D) from 4-(2-methoxy-ethyl)-2-oxo-piperidine-4-carboxylic acid ethyl ester (1 g), dimethylaluminium chloride (1 M in hexane, 17.4 ml) and 4-(2,2,2-trifluoro-ethoxy)-phenylamine (1.25 g). MS (ESI): 343.12 (MH+).

Herkunft & Nachweise