HCID 67536381, Verbindung → 6alpha-Methylandrostane-3,17-dione
Reaktionsgleichung
C1COC23OCCOC2([C@]2(CC[C@H]4[C@@H](C[C@H](C)C5[C@]4(C)CCCC5)[C@@H]2C3)C)O1.[CH2:29]=[C:30]1[CH:47]2[C@:42]([CH3:49])([CH2:43][CH2:44][C:45](=[O:48])[CH2:46]2)[C@@H:41]2[C@H:32]([C@H:33]3[C@@:37]([CH2:39][CH2:40]2)([CH3:38])[C:36](=[O:50])[CH2:35][CH2:34]3)[CH2:31]1>>[CH3:29][C@@H:30]1[CH:47]2[C@:42]([CH3:49])([CH2:43][CH2:44][C:45](=[O:48])[CH2:46]2)[C@@H:41]2[C@H:32]([C@H:33]3[C@@:37]([CH2:39][CH2:40]2)([CH3:38])[C:36](=[O:50])[CH2:35][CH2:34]3)[CH2:31]1Komponenten
3
Versuchsvorschrift
The title compound II-ai was prepared in 94% yield from 3,3:17,17-bis(ethylendioxy)-6α-methylandrostane by the procedure described above for the preparation of 6-methyleneandrostane-3,17-dione (II-ac, Prepn. 13). The combined organic extracts were washed with H2O, dried and evaporated to dryness. 1H-NMR (300 MHz, acetone-d6, ppm from TMS): δ 2.77-0.75 (21H, m), 1.18 (3H, s), 0.98 (3H, d), 0.90 (3H, s).
Aufarbeitung
- washThe combined organic extracts were washed with H2O