5-Bromo-2-acetylsalicylic acid → 2-Acetoxy-5-bromo-N-(4,5-diethyloxazol-2-yl)benzamide
Reaktionsgleichung
[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:11]([Br:14])=[CH:10][C:6]=1[C:7]([OH:9])=O)(=[O:3])[CH3:2].[NH2:15][C:16]1[O:17][C:18]([CH2:23][CH3:24])=[C:19]([CH2:21][CH3:22])[N:20]=1>>[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:11]([Br:14])=[CH:10][C:6]=1[C:7]([NH:15][C:16]1[O:17][C:18]([CH2:23][CH3:24])=[C:19]([CH2:21][CH3:22])[N:20]=1)=[O:9])(=[O:3])[CH3:2]Komponenten
3
Versuchsvorschrift
Using 2-acetoxy-5-bromobenzoic acid and 2-amino-4,5-diethyloxazole as the raw materials, the same operation as the example 24 gave the title compound. (2-Acetoxy-5-bromobeazoic acid: refer to Eur. J. Med. Chem., 1996, 31, 861.)
Quellen und Nachweise
- ORD-Eintrag
- ord-401a22af503d4fb59fae26283c50caa8
- Quelldatensatz
- uspto-grants-2012_01