HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzenamine, 3,5-bis(trifluoromethyl)- → N1,N3-Bis[3,5-bis(trifluoromethyl)phenyl]-4-hydroxyisophthalamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzenamine, 3,5-bis(trifluoromethyl)- | HCID 9480 | — |
| Edukt | 4-Hydroxyisophthalic acid | HCID 12490 | — |
| Edukt | Phosphorus trichloride | HCID 24387 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | N1,N3-Bis[3,5-bis(trifluoromethyl)phenyl]-4-hydroxyisophthalamide | HCID 86595535 | 25% |
Reaktionsschritte
Using 4-hydroxyisophthalic acid (182 mg, 1 mmol), 3,5-bis(trifluoromethyl)-aniline (687 mg, 3 mmol), phosphorus trichloride (87 μl; 1 mmol) and toluene (10 mL), the same operation as the example 16 gave the title compound (151 mg, 25.0%) as a white crystal.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08097759B2 |
| Quelldatensatz | uspto-grants-2012_01 |
| ORD ID | ord-a2d473b40ca34d3aabb73d88d0911467 |
| Quellennotiz | uspto-grants-2012_01 |