17,17-Bis(ethylendioxy)-6-methyleneandrostane → HCID 86635586, Verbindung

HRID 42115Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 42115
[CH2:1]1[CH2:14][O:13][C:8]23[O:9][CH2:10][CH2:11][O:12][C:3]2([C@:4]2([CH2:27][CH2:26][C@H:25]4[C@@H:15]([C:16](=O)[CH2:17][CH:18]5[C@:23]4([CH3:24])[CH2:22][CH2:21][CH2:20][CH2:19]5)[C@@H:6]2[CH2:7]3)[CH3:5])[O:2]1.[CH2:29]1COC23OCCOC2([C@]2(CC[C@H]4[C@@H](CC(=C)C5[C@]4(C)CCCC5)[C@@H]2C3)C)O1>>[CH2:1]1[CH2:14][O:13][C:8]23[O:9][CH2:10][CH2:11][O:12][C:3]2([C@:4]2([CH2:27][CH2:26][C@H:25]4[C@@H:15]([C:16](=[CH2:29])[CH2:17][CH:18]5[C@:23]4([CH3:24])[CH2:22][CH2:21][CH2:20][CH2:19]5)[C@@H:6]2[CH2:7]3)[CH3:5])[O:2]1

Komponenten

3

Edukt 2

HCID 6753593917,17-Bis(ethylendioxy)-6-methyleneandrostaneHCID 6895071317,17-Bis(ethylendioxy)androstan-7-one

Produkt 1

HCID 86635586HCID 86635586, VerbindungAusbeute 85 %

Versuchsvorschrift

The 3,3:17,17-Bis(ethylendioxy)-7-methyleneandrostane was prepared in 85% yield from 3,3:17,17-bis(ethylendioxy)androstane-7-one by the procedure described above for the preparation of 3,3:17,17-bis(ethylendioxy)-6-methyleneandrostane (Prepn. 13). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness. 1H-NMR (300 MHz, acetone-d6, ppm from TMS): δ 4.67 (1H, m), 4.60 (1H, m), 3.86 (8H, m), 2.20-1.10 (20H, m), 0.97 (3H, s), 0.86 (3H, s).

Aufarbeitung

  1. washThe combined organic extracts were washed with H2O
  2. dry with materialdried over Na2SO4
  3. customevaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-d65ee499a5f84b95b021017cea42cfca
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08536160B2

Notizen zur Reaktion

Wird geladen…