Ethyl 2-amino-4-phenyl-1,3-thiazole-5-carboxylate → 2-[2-Hydroxy-5-(1-pyrrolyl)benzoyl]amino-4-phenylthiazole-5-carboxylic acid ethyl ester
Reaktionsgleichung
[OH:1][C:2]1[CH:10]=[CH:9][C:8]([N:11]2[CH:15]=[CH:14][CH:13]=[CH:12]2)=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH2:16]([O:18][C:19]([C:21]1[S:25][C:24]([NH2:26])=[N:23][C:22]=1[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)=[O:20])[CH3:17]>>[CH2:16]([O:18][C:19]([C:21]1[S:25][C:24]([NH:26][C:4](=[O:6])[C:3]2[CH:7]=[C:8]([N:11]3[CH:15]=[CH:14][CH:13]=[CH:12]3)[CH:9]=[CH:10][C:2]=2[OH:1])=[N:23][C:22]=1[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)=[O:20])[CH3:17]Komponenten
3
Versuchsvorschrift
Using 2-hydroxy-5-(1-pyrrolyl)benzoic acid and 2-amino-4-phenylthiazole-5-carboxylic acid ethyl ester as the raw materials, the same operation as the example 195(3) gave the title compound.
Quellen und Nachweise
- ORD-Eintrag
- ord-a122a864a547498e8ea6613f3e562c4d
- Quelldatensatz
- uspto-grants-2012_01