2-Fluoro-4-(methylsulfanyl)aniline → Methyl 2-(2-fluoro-4-(methylthio) phenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate

HRID 421918Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 421918
Cl[C:2]1[N:3]([CH3:13])[C:4](=[O:12])[CH:5]=[CH:6][C:7]=1[C:8]([O:10][CH3:11])=[O:9].[F:14][C:15]1[CH:20]=[C:19]([S:21][CH3:22])[CH:18]=[CH:17][C:16]=1[NH2:23]>>[F:14][C:15]1[CH:20]=[C:19]([S:21][CH3:22])[CH:18]=[CH:17][C:16]=1[NH:23][C:2]1[N:3]([CH3:13])[C:4](=[O:12])[CH:5]=[CH:6][C:7]=1[C:8]([O:10][CH3:11])=[O:9]

Komponenten

3

Edukt 2

HCID 220256172-Fluoro-4-(methylsulfanyl)anilineHCID 57442171Methyl 2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate

Produkt 1

HCID 66673753Methyl 2-(2-fluoro-4-(methylthio) phenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate

Versuchsvorschrift

Methyl 2-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate was prepared from methyl 2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate and 2-fluoro-4-(methylthio)benzenamine as described in Step C of Example 153.

Quellen und Nachweise

ORD-Eintrag
ord-268008f876dd41e984237db633d8cc36
Quelldatensatz
uspto-grants-2012_01
Patentnummer
US08101611B2

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