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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 42373Erstellt: 24. Oktober 2026

Dimethylformamide → N'-(6-oxo-7-phenyl-5,6-dihydro-1,5-naphthyridin-2-yl)propanohydrazide

https://huagongshe.com/de/reaction/42373

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktDimethylformamideHCID 6228—
EduktDiisopropylethylamineHCID 81531—
Edukt6-Hydrazinyl-3-phenyl-1,5-naphthyridin-2(1H)-oneHCID 67069008—
ProduktN'-(6-oxo-7-phenyl-5,6-dihydro-1,5-naphthyridin-2-yl)propanohydrazideHCID 67094058—

Reaktionsschritte

To a mixture of 6-hydrazino-3-phenyl-1,5-naphthyridin-2(1H)-one (7-2) (70 mg, 0.277 mmol) and DIPEA (0.2 mL, 1.15 mmol) in DMF (3 mL) was stirred at room temperature for 0.5 hours. The solvent was removed under reduced pressure to give N′-(6-oxo-7-phenyl-5,6-dihydro-1,5-naphthyridin-2-yl)propanohydrazide (7-3) as yellow solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08536193B2
Quelldatensatzuspto-grants-2013_09
ORD IDord-c3a78af3655f4404a3368cd7f41557c9
Quellennotizuspto-grants-2013_09