Piperidine → 1-Piperidinesulfonamide
Reaktionsgleichung
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[S:7](N)([NH2:10])(=[O:9])=[O:8]>O1CCOCC1>[N:1]1([S:7]([NH2:10])(=[O:9])=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Piperidine (3.0 g) and sulfamide (5.93 g) in 1,4-dioxane (100 ml) were heated at reflux for 24 h. The solvent was evaporated under reduced pressure and the resulting solid suspended in CHCl3. The suspension was filtered and the filtrate concentrated in vacuo to afford the subtitle compound as a white solid. Yield: 3.85 g.
Aufarbeitung
- temperatureat reflux for 24 h
- customThe solvent was evaporated under reduced pressure
- filtrationThe suspension was filtered
- concentrationthe filtrate concentrated in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-ee0d5e1762a847a1929db3d27db38938
- Quelldatensatz
- uspto-grants-2012_01
- Patentnummer
- US08106063B2
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