methyl 1H-indazole-3-carboxylate → 1h-Indazole-3-carboxylic acid,6-bromo-1-(1-methylethyl)-,methyl ester

HRID 424814Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 424814
[CH3:1][O:2][C:3]([C:5]1[C:13]2[C:8](=[CH:9][C:10]([Br:14])=[CH:11][CH:12]=2)[NH:7][N:6]=1)=[O:4].CO[C:17]([C:19]1[C:27]2C(=CC=CC=2)NN=1)=O>>[CH3:1][O:2][C:3]([C:5]1[C:13]2[C:8](=[CH:9][C:10]([Br:14])=[CH:11][CH:12]=2)[N:7]([CH:19]([CH3:27])[CH3:17])[N:6]=1)=[O:4]

Komponenten

3

Edukt 2

HCID 657476methyl 1H-indazole-3-carboxylateHCID 46784006Methyl 6-bromo-1H-indazole-3-carboxylate

Produkt 1

HCID 667041921h-Indazole-3-carboxylic acid,6-bromo-1-(1-methylethyl)-,methyl ester

Versuchsvorschrift

The title compound is prepared essentially as described in procedure 1d WO2005/080389 substituting 6-Bromo-1H-indazole-3-carboxylic acid methyl ester for 1H-indazole-3-carboxylic acid methyl ester. ES/MS m/e 296.0 (M+1).

Quellen und Nachweise

ORD-Eintrag
ord-58b772b43d04489db8d59bd6a348537a
Quelldatensatz
uspto-grants-2012_01
Patentnummer
US08106077B2

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